Huxley and Hodgkin's researches were concerned largely with studying the exchange of sodium and potassium ions that causes a brief reversal in a nerve cell's electrical polarization; this phenomenon, known as an action potential, results in the transmission of an impulse along a nerve fibre. Apart from the researches directly mentioned in the Nobel citation, Huxley made contributions of fundamental importance to knowledge of the process of contraction by a muscle fibre. He published many important papers in periodicals, particularly in the Journal of Physiology. His Sherrington Lectures were published as Reflections on Muscle (1980). |
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