In his prizewinning research, Lwoff showed that, after infection, the virus is passed on to succeeding generations of bacteria in a noninfective form called a prophage. He demonstrated that under certain conditions this prophage gives rise to an infective form that causes lysis, or disintegration, of the bacterial cell; the viruses that are released upon the cell's destruction are capable of infecting other bacterial hosts. Lwoff also discovered that vitamins serve both as growth factors for microbes and as coenzymes. Among his written works are Problems of Morphogenesis in Ciliates (1950) and Biological Order (1962). After World War II Lwoff won the Medal of the Resistance for work in
the French underground. He was also made an officer of the Legion of
Honour. |
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