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German biochemist who, along with Johann Deisenhofer and Hartmut Michel,
received the Nobel Prize for Chemistry in 1988 for their determination
of the structure of a protein complex that is essential to photosynthesis
in bacteria. Huber was an internationally recognized expert in the use of X-ray
diffraction to determine the atomic structure of complex molecules such
as proteins. Once a protein has been reduced to a pure crystalline form,
its atomic structure can be deduced by analyzing the manner in which
the crystal's atoms scatter a beam of X rays. Huber and his colleagues
used this technique to determine the structure of a protein complex
(called a photosynthetic reaction centre) that is essential to photosynthesis
in certain bacteria. By 1985 the three scientists had succeeded in describing
the complete atomic structure of the protein. Although bacterial photosynthesis
is somewhat simpler than that carried on by plants, the scientists'
work significantly increased the understanding of the mechanisms of
photosynthesis in general.
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